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King Saud University’s Dr. Nasser Al-Rashid Chair of Ophthalmology, whose research team is led by Dr. Ahmed M. Abu El-Asrar, has seen quite a few successes and scientific achievements over past years, while supporting and strengthening the University’s mission of establishing international research partners of excellence.
One collaboration in particular, with University of Leuven’s Rega Center for Medical Research, located in Belgium, has recently resulted in a high-profile research article being published in the April issue of Immunobiology, a distinguished scientific journal.
In the April 7, 2011 article, CXC chemokine expression profiles in aqueous humor of patients with different clinical entities of endogenous uveitis, the KSU and Rega Center researchers looked at the role of CXC chemokines in patients with uveitis, which is the inflammation of a part of the eye called the uvea. People with uveitis may experience redness of the eye, blurred vision, sensitivity to light, dark, floating spots along the visual field or eye pain.
From the data of their study, the Saudi-Belgian research team has become the first to show that the levels of the neutrophil chemoattractant GRO-α is elevated in the thick watery substance filling the space between the lens and the cornea (i.e. aqueous humor) from patients with endogenous uveitis.
The research has, as it were, caught the eye of the science community, being recognized by the international scientific commission Target Intelligent Service as valuable research from which pharmaceutical companies can develop new techniques to treat immune diseases.
Such scientific successes are testament to the inestimable value of institutes of excellence cooperating and exchanging scientific research expertise, experience and resources, which supports and enriches King Saud University’s mission.
The research team included the following members:
- Dr. Ahmed M. Abu El-Asrar, KSU
- Dr. Saleh A. Al-Obeidan, KSU
- Dr. Dustan Kangave, KSU
- Dr. Ghislain Opdenakker, K.U. Leuven
- Dr. Karel Geboes, K.U. Leuven
- Dr. Jo Van Damme, K.U. Leuven
- Dr. Sofie Struyf, K.U. Leuven